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Infectious mononucleosis (also known as EBV infectious mononucleosis or Pfeiffer's disease and colloquially as kissing disease - from its oral distribution - or as mono in North America and as glandular fever in other English-speaking countries) is an infectious, very widespread viral disease caused by the Epstein-Barr virus, which well over 90% of all adults are exposed to at some point in their life. Most people are exposed to the virus as children, when the disease produces no noticeable symptoms or only flu-like symptoms. In underdeveloped countries, people are exposed to the virus in early childhood more often than in developed countries, which is why the disease in its observable form is more common in developed countries, where it is most common among high school and college students. Especially in adolescents and young adults, the disease is characterized by fever, sore throat and fatigue, along with several other possible signs and symptoms. It is primarily diagnosed by observation of symptoms, but suspicion can be confirmed by several diagnostic tests. The syndrome was described as an infectious process by Emil Pfeiffer in 1889. Mononucleosis has a set of common symptoms that are usually presented in the individual with the disease. The classical symptoms are a sore throat, fever, fatigue, weight loss, malaise, pharyngeal inflammation and petechiae, and common signs include lymphadenopathy (enlarged lymph nodes), splenomegaly (enlarged spleen), hepatitis (refers to inflammatory cells in the liver) and hemolysis (the bursting of red blood cells). Older adults are less likely to have a sore throat or lymphadenopathy, but are instead more likely to present with hepatomegaly (enlargement of the liver) and jaundice. Rarer signs and symptoms include thrombocytopenia (lower levels of platelets), with or without pancytopenia (lower levels of all types of blood cells), splenic rupture, splenic hemorrhage, upper airway obstruction, pericarditis and pneumonitis. Another rare manifestation of mononucleosis is erythema multiforme. Mononucleosis is sometimes accompanied by secondary cold agglutinin disease—an autoimmune disease in which abnormal circulating antibodies directed against red blood cells can lead to a form of autoimmune hemolytic anemia. The cold agglutinin detected is of anti-i specificity.[10] Patients with infectious mononucleosis are sometimes misdiagnosed with a streptococcal pharyngitis (because of the classical clinical triad of fever, pharyngitis and adenopathy) and are given antibiotics such as ampicillin or amoxicillin as treatment. Some studies indicate that approximately 80-90% of patients with acute Epstein Barr virus infection treated with such antibiotics develop a red, diffuse rash. Infectious mononucleosis occurs with infection by the Epstein-Barr virus.[12] A similar condition can be caused by cytomegalovirus. Because of this, some sources say that infectious mononucleosis is "usually caused by the Epstein-Barr virus". Other sources reserve a different term, "cytomegalovirus mononucleosis," for mononucleosis caused by cytomegalovirus. Some sources state that infectious mononucleosis can also be caused by toxoplasmosis or viral hepatitis.>BR> The infection is spread via saliva and has an incubation period of 4-7 weeks. The virus replicates first within epithelial cells in the pharynx (which causes sore throat), and later primarily within B cells (which are invaded via their CD21). The host immune response involves cytotoxic (CD8-positive) T cells against infected B lymphocytes, resulting in enlarged atypical lymphocytes (Downey cells). When the infection is acute (recent onset, instead of chronic), heterophile antibodies are produced. In Europe, bio-oxidative therapy has been found to be effective in management of this disease! For more information on how to stay healthy with bio-oxidative therapy . . . . . CLICK HERE! I CHOOSE TO LIVE - HEALTHCARE Where can I get the proper instructions? The I CHOOSE TO LIVE - HEALTHCARE instruction manual will give you the precise steps, and precautions, that you will need to achieve optimum results safely. The therapy plan is simple to use, and follow. Just click below to order your e-book instruction manual. I Choose to Live . . . . HealthCare instruction manual
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